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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457f45e8aeba0a97f33fd17055a68b736c9b347e41824c8084b639d08242e8c6' 
  AND token = '0S8jNE7e+xBm+8CGtubhfvs0tClTUf6mSUBDtWMMBds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}