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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '496d90cfa5ab008e5b8073e4f8a6422af092422920aa19003aecf28ee98a7edd' 
  AND token = 'n7eMiZB5p/MEpw+SH1EnOLEiUJRiKuxkr+bHx6pyEQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}