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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29a7280c520cb1bb11be091c5402868d3b75d5b586f3d17133d9b1a43715499f' 
  AND token = 'qgwzBKSA3hpNOF/mR1gzqOcZzDITn0TK8cw2TPrq0KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}