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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42740484fd15f3625a5370ded47ce36a723cc084a8849637b51a8b76a4ff0395' 
  AND token = '6lBwZgJsRT3d3CfoUzJ11zOLknwNKn5SMTyib0XvUAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}