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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646fb5d2fdc3a361e8648df4366dea0adb3a35a4d8d037ee58b22d80d1afd8b2' 
  AND token = 'INKIuFOwjeb99NdDBnsUlsKOYqqYwcpt31QgLECHpO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}