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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7cf95c8d385094154975d12fed3ecb2d1e9dca95521d3a4928161645d4dd64b' 
  AND token = 'xkSVGZtXc//ehzRbdxm1azGavjsNgCJ6bSv6poMI+4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}