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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88cdde0a3fc8a925f2e1aa1c8e44819b596af2eb729bc2225c0a66c854227939' 
  AND token = 'KSaVRH6bLy8Ft6ymbVUriZJT2X7NqHSvPsoyb98/Eqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}