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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37b0ee89afdfc390c75e9382a0f54578701f5bdee601754bd7654e87e53a8c99' 
  AND token = 'EcSScDuZMqJ9hqcZ3IkX/oNYLVbBigU+XEQqnnkQ+sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}