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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e61dd7274dbfba14c57953a7e3feca4d5c7307f3936981f5f5cff402c4a49e9' 
  AND token = 'ZFPV1OSjB3erEMuwbE1K4hbNGGgKoJ6PON2hRASUApI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}