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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48a639ed666080753cbb62a9d6178485750e389a264c36913a581b9add07eac' 
  AND token = 'BCXKp3EsJUmTPckBUbPkUAKMMcp8pJiVIdWtV+37axM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}