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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95e5950d2bf2b67275fdb7534d948bfc8f2cac990f6b975707a5f4ed81ef285' 
  AND token = 'rICthKkPupsOQnFapx1UOKNWgEWAEatWVNNH1TCaHIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}