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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e3b1091c7e2fdfbabff8829540983bf63ec6b9716b51570f1d326e33f436d9' 
  AND token = 'EEtpRNLsY9owTHlA3F28p4alN1X/nJe2pmNk92Xa83s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}