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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380f5bde868eac10f9d464fcab77958a838a2d8e40bdbd8035e3577bda9fa6d3' 
  AND token = 'k7VqdZb9fwgM5p40X8/kBlxJ/p43wGLh8p1dI28D+wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}