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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441613bc76fee383e38a861a2c1c594786f1d90b17e4d89f9425fdfa389d0803' 
  AND token = 'ffIp4TJwlEnIUoQP7wtM16YupY1mRUSgU0kH+D+ODh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}