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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1800206d4f4e6533593e191c0d294e61749e93678cac65d9f1443559fc794540' 
  AND token = 'pW4EU3+96nQEv+PErxaoln2enueJSMMi4DA9Ma+O8UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}