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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b4d2d7e9534c6ca879cd20a1da4b1dcf84328e78985da332e9d89d709c96db' 
  AND token = 'b1QNoqCccAQVrS1dIyoNK2ZfSjtmmSq5/BWxuUxRjVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}