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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad1dc8ca7a9d9b5c5d17a2b56d09c68702474094afc1c5317f1fca156561c68' 
  AND token = 'vwWOB/I1y9X2RufALdaeqMAFTDVr7V0VFrJFBcdjjwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}