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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd892cbd86028cda974b58839defc231e45dbe98f02b2ea24ae0af9c1763900' 
  AND token = 'F4Z6sVj/Jsw1fwkUwZcQQqTgG8wE/7DA9U3XSL+OQ9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}