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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad3a89e18458baad9f14c33f10250fe1b198eeec7faab78c4ec216db5cbb44b' 
  AND token = 'i0imAC+bPCnoeTbhXVRACykdg4uUYEkiXk7Fk98Wi5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}