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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a89358881f37fc24052fe043bf63babd3a2a8e6707471b59dffa2a0af3a9328' 
  AND token = 'TQs3+VHN/ZdJ8kGqBptPsPPr7rt1prlHBmld/kLtVjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}