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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29cca8a80430406c2c2a6ece65e8ace72cef73836f7d84fa1959c9ae4acfc005' 
  AND token = 'l17u+oaIxMkiR0o6sz2+U/h2wmYeFaMA382ljcPLMBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}