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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da0116dd274e9fe1f1e48ba19da194c7e6948e582ed5cb31b2a129e1e67e3303' 
  AND token = '68pqyF+TkSbsB9zMH+35ohTWj4OU87tMdW3vDN1M40A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}