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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d5cf0dd219fac792101dfbd80101cd8fa8ca170e6309d13349d86291e01c866' 
  AND token = 'OS2eDlWi4t/wl1IniKEx943fxFqGW6E0TlvFk+eSYDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}