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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f141b0d1535fd4a410bb50d0c750294c365d91ebfeb182211aea7768c8dfa0f' 
  AND token = 'yB9EuL/wMKF2FSor6TLQiQq9De3yrUOYjDOWOSo2NXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}