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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f266f14ba06372c01a6f6e586d92b665b9fe38d9395b81ac9bd8e1d4323c7680' 
  AND token = '45qVZt44xfnNlwnEHornpZbzJVostZeM80551FFvNag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}