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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e92e1c21b39b6307d5783fbb1fb00ae2ff352a7b206dad510ad062721d265c5b' 
  AND token = 'j611Gd8GPzKGkAg4gdaudfQt9eW3QxKYXE7YBGYwiDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}