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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1339bedf2c019e23906505959e05f248d3f07eb1182458bcad1cd74fda4e421' 
  AND token = '3YJ1SKe1ySJ9Q6cRGoQpLo+exE0cxZeiCRNn7INuHE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}