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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e197c2c3ab33bcab6dca21f2515c0665615cb00845b8488b5b8d7cbaba6307f4' 
  AND token = 'aA3O2nFPfQdAIUaUebzaEGK/vO8BBjIxAaD0BnuqiCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}