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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74129fc2406e273788a9fa8abc976c2a027a48d966bc3b3a79f7554e127900a1' 
  AND token = '/wyZrwsXhZ/N/SjfsH4Ky8sZIdtM3jL+YHTRtQCamko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}