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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '086cacb193ca31ad7bb9c431de82e335649318b5d55ebdac3b41e0e1735ee642' 
  AND token = 'Ufr8Ys1OXb7DWRhkypKCHUVBm4zBOv3qaPfCbcPgZMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}