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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffb5d9e891c99e33a8efcb333e9627e388a957de6fe3597fb7bf7f717a957273' 
  AND token = 'Q2mrckY995x6nfACre/WYX9uyM44kq4XSKe8J5EiJC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}