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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'beb28b2c2d584fd8954a8b9b918c97eda2f8c8a9b29e7ed96e5cb3437478a865' 
  AND token = 'V+LrGYlPLywxbSEPUP7S78MZIxVaxGw9Ma1myrGwTQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}