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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e3be3d44e2407cf326e7dba06e7f0214372b4cf33422ee381d3907ccd4e1984' 
  AND token = 'rOwj1/NnNeoqeKCyWEdpsiMv63uc4hL4V3covjQXXqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}