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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95bcaec8d086e1e7628248694e8394e0649d2ecdc7c1019580f7df85b24bba59' 
  AND token = 'p1eYSGi1LGe71LwD96u2MUBmQIma39L5jxLEbD9LOeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}