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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d3e86c6a2e460714eeb5392a2c32ecd626d79593eedb0f765100ce1d6df644' 
  AND token = '7mFhvQUGHdRy2XETOEp/xCGCzUq2Pc872dazGqXkofo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}