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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b716e5ff49a0f7004e696153c7b95fd6d31d70ac1928fd6b1afaa006221d997d' 
  AND token = 'YUSyrdkTjirKGy367otOmsgfmXj9xVEILY9QgdM9BiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}