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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad64232900ee85f22ddba2f8769f1e4d5ea07b9e8cde2ea942bedc959db5430b' 
  AND token = 'jaEfNQJBS5RqYeMmvpMfI4IOC7R3vV5yp6YmR3xE+Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}