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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8a86e7ad3a3ad70b4b6cd4c048a0d0e53c861f02226767cc508b17016acac5d' 
  AND token = 'FWk+0YVzX3NbaQeC8wYUAy1AARkx8Z2/IOFTqaIkMM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}