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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bacee61b099b5356543e324326ae34b10a002f544b48f97d19f2c117e46b7e09' 
  AND token = 'ENZP+9CXzI8gESkJdzZvrjIDvNRlQxI0yj4cgFSS4mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}