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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08dfb2171553dbea8a8768ff1c690af3a1a29525a9a4632c9e36c9790e3787f0' 
  AND token = '7d5E/5rUrzCrUVsSum+z0gXCADaPeNlt1T1E8XsQ1WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}