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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d044b99e1fda64b5bffa9e048f09d3400c43932be9bce700007d8ea62696485' 
  AND token = 'MuCchUBt6Vt92+gEIwAyQ2TdC/9iNZbmVyEbzsQhkUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}