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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d421892d4a7800a01cc7627f06ef412e858f3d5c8267be70717b14915734797' 
  AND token = 'cqxoduYx5bwjoe9Hk4MvimREnUWqmLmM4of7AVKcL3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}