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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38562dbf7097030d92c8583b88f69edb683ad6073b999728990049007e1bd049' 
  AND token = 'GvzWF455QZA7LmPuNxbXtK6LPfJdfIQVNtsZUiyBOz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}