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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a67f5337ff2f4f5a807e8f3cccdb93f3a2df27b28c797c34d7d1627209d11a20' 
  AND token = '5U++XkmH3u5/CqBYdGQQry6K+rBDuU3OwMHefOhaGI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}