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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05a0d3324194db923f4812f9be560e9547483fbe57a3cf66b93bd90749e06e22' 
  AND token = 'a5dbLUIYI+s9KW2HxDFerdj1fx1G+bCTy7W2puUOoBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}