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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9710765f080e8c1172378cd7d3fb49a7892697f5456cb059354e5b6a66a6cfe' 
  AND token = '0ZiIVOpQv7YDh97Vx/oC7iHD7PnmQ7DT0yAxMDRjUkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}