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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246d27bbb03d411ce8a4a7dfb24528a5724dcc3c99d74102981c106b499dc603' 
  AND token = 'JWpJc27o2LFFPNwg46wpjVXGXkkMTRpEBz6na2wfpLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}