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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c5d2460894aecf7d24a6357f19868236c3e5ec85032f0eaee5789ecb1b7ded5' 
  AND token = 'ZaTZXnKtRRfVm8D96LDwUmYnW6qnIy4QM4PM7glrUj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}