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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0528a2af0000fdbf6132823619f71e39c13d2938f901bb2b0d7f3997222a2015' 
  AND token = 'N3yNOQCa9vzq4Mu7ojlU4AE1VdT6eDft5FUh0zdX8zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}