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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '300ac1f6d5f7ffe22a205c637ad18afef28aec2a54a7f7b8a4feb535906a5d91' 
  AND token = 'VILNabW+DshMlc8bVL20LVokqI5W7qU/RzAojPPl3XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}